Rajneesh Kumar Sharma, a research scholar, social worker, dedicated him
self for the development of Homoeopathy. He has presented many articles
in scientific journals with evidence-based documents. Here the author
shares his experience with adenocarcinoma of oesophagus with histopatholgical
of oesophagus also known as Barrett’s carcinoma is common among
causian males. The incidence is more past the age of forty. The location
is usually the lower part of the oesophagus affecting the columnar mucosa
above the gastro oesophageal junction
Most oesophageal adenocarcinomas arise in Barrett’s oesophagus.
Many adenocarcinomas presumed to be originating from the gastric cardia,
may actually be arising in a short-segment Barrett’s oesophagus.
Only about half of patients relate symptoms of chronic gastro oesophageal
reflux. The radiological appearance is highly variable. May present as
stricture, ulcer or polypoid mass.
In histopathology morphological range as adenocarcinoma of the stomach,
from well-differentiated adenocarcinoma with relatively uniform gland
formation to poorly differentiated tumors with only focal gland formation
and/or mucin formation. Signet ring cell carcinoma may also occur. Major
prognostic factor is clinical stage. The majority of tumors are known
in late stage, hence poor overall survival.
A female aged 50 years with the habit of beetle chewing and tobacco habit
complained regurgitation of food and dysphagia. She was much debilitated
and scared about her disease. She stays alone in the house.Past history
revealed Herpes zoster in the past few years back. She had three abortions.
Earlier she had spicy food and desires for sweets and hot food always.
Family history is nothing relevant.
The Histopathogical Report 12-12-2003
The oesophageal specimen shows hyper cellular epithelium and loss of nuclear
polarity. Pleomorphic nuclei, predominantly enlarged, with marked hyperchromasia,
chromatin clearing and clumping, mitoses, and prominent nucleoli are also
marked. Crowded irregular glands, possibly with luminal infoldings and
possibly villiform surface are evident.
Impression- Barrett’s esophagus with high-grade dysplasia.
* See the slide with report printed at the visual corner-Before treatment
Based on the mental symptoms and desires aversions.
Lycopodium 200 Alternate day
Hydrastis Q TDS
General improvement better
Phosphorus 1 M one dose.
The specimen sent as oesophageal piece shows features of necrosed tissue
with shriveled cells. Some cells show hypercellularity to mild degree.
No pleomorphism seen in different neucli except hyperchromatism in some.
Impression- faint to mild degree of dysplasia showing necrosis and hypocellular
The regression of the carcinoma with necrosis of the cancer cells.
*See the slide with report printed at the visual corner-After treatment
The patient keeps good health now and being monitored